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咬肌源性前庭诱发肌源性电位（masseter vestibular evoked myogenic potentials,mVEMP）通过听觉-咬肌和前庭-咬肌反射通路记录反应，可用作补充测试评估前庭三叉神经通路功能，可能有助于诊断快速眼动睡眠行为障碍、多发性硬化症、肌萎缩侧索硬化症和帕金森病中的脑干损伤。mVEMP作为临床和放射成像的辅助手段，有一定的临床价值和研究意义。本文对mVEMP机制、检测方法及临床应用进行综述。
Abstract：Masseter vestibular evoked myogenic potentials(mVEMPs), as responses involving the auditory-masseter and vestibular-masseter refiex pathways, can be used as a complementary test to assess function of the vestibular trigeminal nerve pathway to help diagnose brain stem damage in REM sleep behavior disorders, multiple sclerosis, amyotrophic lateral sclerosis and Parkinson's disease. as a supplement to clinical and radiographic examinations, mVEMP has certain clinical values and can facilitate research. This article reviews its neural mechanisms and potential clinical applications.
[1] Murofushi T, Matsuzaki M, Wu CH. Short tone burst-evoked myogenic potentials on the sternocleidomastoid muscle:are these potentials also of vestibular origin?[J]. Arch Otolaryngol Head Neck Surg,1999, 125(6):660-664.
[2] Nagarajan A, Sinha SK. Masseter vestibular evoked myogenic potentials:a new tool to assess the vestibulomasseteric reflex pathway[J]. J Otol, 2024, 19(1):46-54.
[3] Vignesh SS, Singh NK, Rajalakshmi K. Tone burst masseter vestibular evoked myogenic potentials:normative values and testretest reliability[J]. J Am Acad Audiol, 2021, 32(5):308-314.
[4] Meier-Ewert K, Gleitsmann K, Reiter F. Acoustic jaw reflex in man:its relationship to other brain-stem and microreflexes[J].Electroencephalogr Clin Neurophysiol, 1974, 36(6):629-637.
[5] Deriu F, Tolu E, Rothwell JC. A sound-evoked vestibulomasseteric refiex in healthy humans[J]. J Neurophysiol, 2005, 93(5):2739-2751.
[6] Kiziltan ME, Benbir G, Uzun NA, et al. Auditory-evoked masseter inhibitory refiex[J]. Neurosci Lett, 2010, 475(1):12-15.
[7] Colebatch JG, Halmagyi GM. Vestibular evoked potentials in human neck muscles before and after unilateral vestibular deafferentation[J].Neurology, 1992, 42(8):1635-1636.
[8] Deriu F, Ortu E, Capobianco S, et al. Origin of sound-evoked EMG responses in human masseter muscles[J]. J Physiol, 2007, 580(Pt 1):195-209.
[9] Tolu E, Pugliatti M. The vestibular system modulates masseter muscle activity[J]. J Vestib Res, 1993, 3(2):163-171.
[10] Giaconi E, Deriu F, Tolu E, et al. Transneuronal tracing of vestibulotrigeminal pathways innervating the masseter muscle in the rat[J].Exp Brain Res, 2006, 171(3):330-339.
[11] Deriu F, Tolu E, Rothwell JC. A short latency vestibulomasseteric reflex evoked by electrical stimulation over the mastoid in healthy humans[J]. J Physiol, 2003, 553(Pt 1):267-279.
[12] Deriu F, Podda MV, Chessa G, et al. Trigeminal integration of vestibular and forelimb nerve inputs[J]. Arch Ital Biol, 1999, 137(1):63-73.
[13] Tolu E, Pugliatti M. The vestibular system modulates masseter muscle activity[J]. J Vestib Res, 1993, 3(2):163-171.
[14] Deriu F, Podda MV, Milia M, et al. Masseter muscle activity during vestibular stimulation in man[J]. Arch Ital Biol, 2000, 138(3):205-215.
[15] Hickenbottom RS, Bishop B, Moriarty TM. Effects of whole-body rotation on masseteric motoneuron excitability[J]. Exp Neurol, 1985,89(2):442-453.
[16] Deriu F, Giaconi E, Rothwell JC, et al. Refiex responses of masseter muscles to sound[J]. Clin Neurophysiol, 2010, 121(10):1690-1699.
[17] Cuccurazzu B, Deriu F, Tolu E, et al. A monosynaptic pathway links the vestibular nuclei and masseter muscle motoneurons in rats[J]. Exp Brain Res, 2007, 176(4):665-671.
[18] Manns A, Chan C, Miralles R. Infiuence of group function and canine guidance on electromyographic activity[J]. J Prosthet Dent, 1987,57(4):494-501.
[19] Hattori Y, Shimizu Y, Satoh C, et al. Masticatory motion is controlled in humans by a limited set of muscle synergies[J]. Tohoku J Exp Med,2010, 220(3):217-222.
[20] Tolu E, Caria MA, Chessa G, et al. Trigeminal motoneuron responses to vestibular stimulation in the guinea pig[J]. Arch Ital Biol, 1996,134(2):141-151.
[21] Sangu VS, Munirathinam BR, Singh NK, et al. Usefulness of masseter vestibular evoked myogenic potentials in identifying brainstem dysfunction among individuals with multiple sclerosis[J].Int J Audiol, 2023, 62(7):635-643.
[22] Romero DJ, Jacobson GP, Roberts RA. The effect of EMG magnitude on the masseter vestibular evoked myogenic potential(mVEMP)[J]. J Otol, 2022, 17(4):203-210.
[23] Loi N, Manca A, Ginatempo F, et al. The vestibulo-masseteric refiex and the acoustic-masseteric reflex:a reliability and responsiveness study in healthy subjects[J]. Exp Brain Res, 2020, 238(7-8):1769-1779.
[24] Mat Q, Duterme JP, Tainmont S, et al. Optimizing ocular vestibular evoked myogenic potentials with narrow band CE-chirps[J]. Ear Hear, 2021, 42(5):1373-1380.
[25] de Natale ER, Ginatempo F, Paulus KS, et al. Abnormalities of vestibular-evoked myogenic potentials in idiopathic Parkinson’s disease are associated with clinical evidence of brainstem involvement[J]. Neurol Sci, 2015, 36(6):995-1001.
[26] Magnano I, Pes GM, Pilurzi G, et al. Exploring brainstem function in multiple sclerosis by combining brainstem refiexes, evoked potentials,clinical and MRI investigations[J]. Clin Neurophysiol, 2014, 125(11):2286-2296.
[27] Vignesh SS, Singh NK, Rajalakshmi K. Tone burst masseter vestibular evoked myogenic potentials:normative values and testretest reliability[J]. J Am Acad Audiol, 2021, 32(5):308-314.
[28] De Natale ER, Ginatempo F, Mercante B, et al. Vestibulo masseteric refiex and acoustic masseteric Refiex. Normative data and effects of age and gender[J]. Clin Neurophysiol, 2019, 130(9):1511-1519.
[29] Sato H, Sando I, Takahashi H. Sexual dimorphism and development of the human cochlea. Computer 3-D measurement[J]. Acta Otolaryngol, 1991, 111(6):1037-1040.
[30] Sheykholeslami K, Murofushi T, Kaga K. The effect of sternocleidomastoid electrode location on vestibular evoked myogenic potential[J]. Auris Nasus Larynx, 2001, 28(1):41-43.
[31] Tas Elibol N, Behmen MB, Terlemez?, et al. American speechlanguage-hearing association, 2024. evaluation of masseteric vestibular evoked myogenic potentials in patients with migraine[J].Am J Audiol, 2024, 33(2):510-517.
[32] de Natale ER, Ginatempo F, Paulus KS, et al. Paired neurophysiological and clinical study of the brainstem at different stages of Parkinson's disease[J]. Clin Neurophysiol, 2015, 126(10):1871-1878.
[33] Magnano I, Pes GM, Cabboi MP, et al. Comparison of brainstem refiex recordings and evoked potentials with clinical and MRI data to assess brainstem dysfunction in multiple sclerosis:a short-term follow-up[J]. Neurol Sci, 2016, 37(9):1457-1465.
[34] de Natale ER, Ginatempo F, Laccu I, et al. Vestibular evoked myogenic potentials are abnormal in idiopathic REM sleep behavior disorder[J]. Front Neurol, 2018, 9:911.
[35] Sheykholeslami K, Megerian CA, Arnold JE, et al. Vestibular-evoked myogenic potentials in infancy and early childhood[J]. Laryngoscope,2005, 115(8):1440-1444.
基本信息:
中图分类号:R764
引用信息:
[1]戴秀苹,罗永旺,杜一,等.咬肌源性前庭诱发肌源性电位临床应用进展[J].中华耳科学杂志,2025,23(09):1084-1089.
2025-12-02
2025-12-02